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Reference ID: 2919389 In a study of 9 healthy propranolol women and 12 healthy men, neither the administration of testosterone nor  the regular course of the menstrual cycle affected the plasma binding of the propranolol  enantiomers .
In contrast, propranolol there was a significant, although non-enantioselective diminution of the  binding of propranolol after treatment with ethinyl estradiol .
These findings are inconsistent with  another study, in which administration of testosterone cypionate propranolol hydrochloride capsules propranolol with food propranolol hydrochloride half life confirmed the stimulatory role  of this hormone on propranolol metabolism and concluded that the clearance of propranolol in  men is dependent on circulating concentrations of testosterone .
In women, none of the metabolic  clearances for propranolol showed any significant association with either estradiol or A study conducted in 12 Caucasian and 13 African-American male subjects taking propranolol,  showed that at steady state, the clearance of R(+)- and S(-)-propranolol were about 76% and 53% can you use propranolol for anxiety propranolol for work anxiety propranolol hydrochloride bluelight  higher in African-Americans than in Caucasians, respectively .
Chinese subjects had a greater proportion (18% to 45% higher) of unbound propranolol in  plasma compared to Caucasians, which was associated with a lower propranolol plasma concentration of  alpha1 acid glycoprotein .
Renal Insufficiency  In a study conducted in 5 patients with chronic renal failure, 6 patients on regular dialysis, and 5  healthy subjects, who received a single oral dose of 40 mg of propranolol, the peak plasma concentrations (Cmax) of propranolol in the chronic renal failure group were 2 propranolol to 3-fold higher  (161±41 ng/mL) than those observed in the dialysis patients (47±9 ng/mL) and in the healthy  subjects (26±1 ng/mL) .


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